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There are many more effective, evidence-based ways to control appetite, reduce snacking and lose weight without relying on dietary supplements. Other studies demonstrate similar results, indicating that guar gum may be effective in reducing cravings and overall calorie intake (38). Though these results are promising, larger and longer-term studies must be carried out to understand saffron’s role in appetite reduction and weight loss. Acacia fiber, also known as gum arabic, is a type of indigestible fiber promoted as a means of suppressing appetite and promoting fullness. However, test-tube and animal studies show that guarana extract may boost metabolism and limit fat cell production by suppressing certain genes (29). Summary Currently, no evidence supports the use of Hoodia gordonii for weight loss or reduced appetite.
However, human studies have shown that CLA has little impact on appetite and weight loss. A 12-week study in 62 people demonstrated that 3.9 grams of CLA per day had no effect on appetite, body composition or the number of calories burned (3). Here’s a review of 12 over-the-counter appetite suppressants, their effectiveness and safety.
A review of six studies found that 1.24–3.99 grams of glucomannan per day for up to 12 weeks resulted in short-term weight loss of up to 6.6 pounds (3 kg). Summary Some research shows that garcinia cambogia suppresses appetite and promotes weight loss. A review of 23 studies found that 20–35 mg of synephrine per day increased metabolic rate and had a modest impact on weight loss. Because bitter orange is often combined with other compounds — such as caffeine — in weight loss supplements, it’s difficult to interpret its effectiveness. Bitter orange is a type of orange that contains synephrine, a compound that may be effective in reducing appetite.
Summary Guar gum is a type of fiber that may be effective in reducing snacking between meals and decreasing overall calorie intake. Summary Some evidence supports the use of saffron extract as a way to reduce hunger and lose weight. Summary Guarana — which is especially high in caffeine — may boost metabolism, but more research is needed to determine whether it suppresses appetite or promotes weight loss. Green coffee bean extract is a substance derived from the raw seeds of the coffee plant and is popularly used as a weight loss supplement.  Trenbolon Legal in Deutschland -day study in 49 overweight women found that 2.2 grams of Hoodia gordonii per day taken one hour before meals had no effect on body weight or calorie intake compared to a placebo (22).
For example, a review of 15 studies found that overweight individuals who supplemented with CLA for at least six months only lost an average of 1.5 pounds (0.7 kg) more than people in the control group (4). Though CLA supplements have been shown to promote fat loss in some studies, its impact on weight loss is small. Cutting out processed foods, reducing your overall calorie intake and increasing your activity levels are tried-and-true methods that will put you on the path to weight loss.
ironmaiden  in 28 people demonstrated that garcinia cambogia was more effective at reducing appetite, increasing fullness and decreasing hunger than a placebo (14). However, very few of the dietary supplements listed above have sufficient evidence to suggest effectiveness in reducing appetite. However, several studies demonstrate that doses of up to 500 mg of forskolin per day failed to reduce appetite, decrease food intake or encourage weight loss in overweight individuals (42, 43). Summary Acacia fiber may encourage weight loss by increasing feelings of fullness and suppressing appetite. Similarly, a study in 92 people with diabetes showed that 30 grams of acacia fiber daily for three months significantly reduced belly fat (33). Summary Several research studies have demonstrated that green coffee bean extract may reduce appetite and promote weight loss.
Conjugated Linoleic Acid (CLA) is a type of polyunsaturated fatty acid naturally found in foods like dairy and beef. While  frescina  of appetite suppressants can only be prescribed by a doctor, many are available over the counter. Vander Wal, JS et al. (2005) Short-term effect of eggs on satiety in overweight and obese subjects.” Journal of the American College of Nutrition vol.
Extracts from Hoodia gordonii are used in dietary supplements that claim to reduce appetite and boost weight loss. Bitter orange supplements are marketed to promote weight loss by reducing appetite and are available over the counter. Appetite suppressants are types of supplements that work by reducing appetite, thereby decreasing food consumption and promoting weight loss. While certain supplements — such as acacia fiber, guar gum and chromium picolinate — have been reliably shown to decrease appetite, they may cause adverse side effects, such as headaches, diarrhea and abdominal discomfort.